I‘m surprised how many people look here for help on the .Net 2.0 SerialPort component (reference, which leads to this posting). I have plenty of example code, but I haven’t had time to re-test the project or even try com0com on this 64-bit Windows box. Com0Com (link) does support 64-bit environments, provided that you:
The com0com.sys is a test-signed kernel-mode driver that will not load by
default. To enable test signing, enter command:
bcdedit.exe -set TESTSIGNING ON
What is bcdedit?
No examples for now but my earlier mentioned posting should get you somewhere.